Boone,
The trout don't seem to make any type of "run" search for the KDFW trout movement study on the cumberland river. You'll see that the tagged trout in the study seem to find a home territory and stick close to it. There is some movement in the Fall when some of the fish attempt to spawn, but I wouldn't call it a run. The walleye and stripers do travel up and down the river. Somewhat unpredictable, best bet is to to just keep your eyes and ears open for word that they are biting.
Good luck down there. It is truly God's Country! Can be a tough place to fish some days, other days they'll bite anything you throw at them. Enjoy your trip, watch the release from the dam, take your camera, and go catch fish