Having seen her speak so emphatically about how much she doesn't want to be the VP I do believe she is sincere when saying that she doesn't want it. I have heard her say more then once that what she really would love to do is one day become the commissioner of the NFL. However sometimes people do respond when asked out of duty to their country, so I wouldn't rule it out.

I am a big fan, I think she would be better than Romney (not a real fan of his). My only concern is it opens up to the campaign the rehashing of everything from the Bush administration. Not sure that is the best strategy for beating Obama.