I myself do not fish the main river for the most part until the end of May. There may be a few spots I will hit that hold smallies or spots this time of year but most of your largemouths are going to be in the creeks. River fishing can be easy this time of year if the water levels stay normal and not much flooding happens. Once June hits most of your good fish will start moving back out into the main river. So definately key on the creeks this time of year, but not all creeks are created equal.