Reply With QuoteOriginally Posted by TimE
Thank you for freeing up a ventilator in case I need it. Vaccinated, I might not be able to take advantage of your kind offer.
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Senior Member
Thank you for freeing up a ventilator in case I need it. Vaccinated, I might not be able to take advantage of your kind offer.
Moveon liked this post
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why hasn't someone melted the lab where they created this virus with their gain of function technique?
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Troll on Timmy. No one is listening to your BS anymore.
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Seems pretty clear. I have offered to buy your coward ass breakfast,lunch,or supper several times. You are to big a coward,chickenshit, gutless, spineless Piece of **** to show up.
Your keyboard warrior skills are lackadaisical at best. Your man skills-prove you are a pussy
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Go **** yourself Timmy. You are a lousy piece of ship and can't back up any of your stupid statements. Go crawl back into that sewer hole you came out of.
If I showed up anywhere near you.. you would **** and piss your pants.
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Refused to administer ivermectin to a patient. The AG of the state sent State Trooper to the hospital to try to badger the hospital doctors into giving a patient an unapproved drug to a Covid Patient. This AG needs to be investigated. Ivermectin is only approved as a treatment for parasite infections and is not approved for treating virus infections.
Senior Member
stop spreading lies.
it is approved and listed on the NIH.org website.
it even gives the recommended dosage and side effects.
i'd say remdesivir has killed more than the virus. look at it's side effects. liver and kidney failure.
https://www.covid19treatmentguidelin...bles/table-2e/
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remdesivir is the only FDA approved drug for treating SARS CoV2 virus.
You say its (Sic) approved by you don't say what is approved. What the he(( are you talking about man?
Go back and get a link to whatever it is you are trying to say. NIH.org has a lot of stuff on that web site. Exactly where on that web site does it say what you are talking about?
And I think that there are some other FDA approved Drugs for treating Covid 19 disease. But drugs that are used to treat parasites like ivermectin are not FDA approved for treating patients with Covid 19 disease.
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Nor is any vaccine that is available in United States. A leaky, mutant causing vaccine at that. Did I mention congestive heart failure?
I hope that you wake out of your slumber before # is called, you have lied like a lowly scum maggott. I have only called one person a coward in my entire life, I offered anyone a chance to see that they were scum and liar, you simply wouldn’t show. Your mouth got you in a sling that your a s s couldn’t back up. I understand.
I really hope you do better research than what you have offered for past two years. Some of you should simply be embarrassed by the FACTS coming out.
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since you seem unable to open the NIH.gov table 2e link i provided, here is a copy of what it says.
Table 2e. Characteristics of Antiviral Agents That Are Approved or Under Evaluation for the Treatment of COVID-19
Last Updated: July 8, 2021
Dosing Regimens
The doses listed here are for approved indications or from reported experiences or clinical trials.Adverse Events Monitoring Parameters Drug-Drug Interaction Potential Comments and Links to Clinical Trials Remdesivir The doses and indications listed below come from the FDA product information. Please see Therapeutic Management of Hospitalized Adults With COVID-19 for the Panel’s recommendations on when to use RDV.
For Hospitalized Adults and Children (Aged ≥12 Years and Weighing ≥40 kg)
For Patients Who Are Not Mechanically Ventilated and/or on ECMO:
RDV 200 mg IVa on Day 1, then RDV 100 mg IV on Days 2–5
For patients who do not show clinical improvement after 5 days of therapy, treatment may be extended to up to 10 days.
For Mechanically Ventilated Patients and/or Patients on ECMO:
RDV 200 mg IVa on Day 1, then RDV 100 mg IV on Days 2–10
Suggested Dose in EUAb for Hospitalized Children
For Patients Weighing 3.5 kg to <40 kg:
RDV 5 mg/kg IVa on Day 1, then RDV 2.5 mg/kg IV once daily starting on Day 2
For patients who are not mechanically ventilated and/or on ECMO, the duration is 5 days. If patients have not shown clinical improvement after 5 days, treatment may be extended to up to 10 days.
For mechanically ventilated patients and/or patients on ECMO, the recommended treatment duration is 10 days.
For Patients Aged <12 Years and Weighing ≥40 kg:
Same dose as for adultsNausea
ALT and AST elevations
Hypersensitivity
Increases in prothrombin time
Drug vehicle is SBECD, which has been associated with renal and liver toxicity. SBECD accumulation may occur in patients with moderate or severe renal impairment.
Each 100 mg vial of RDV lyophilized powder contains 3 g of SBECD, and each 100 mg/20 mL vial of RDV solution contains 6 g of SBECD.
Clinicians may consider preferentially using the lyophilized powder formulation (which contains less SBECD) in patients with renal impairment.Infusion reactions
Renal function and hepatic function should be monitored before and during treatment as clinically indicated.
In the FDA product information, RDV is not recommended when eGFR is <30 mL/min. See the Remdesivir section for a discussion on using RDV in people with renal insufficiency.
RDV may need to be discontinued if ALT level increases to >10 times ULN and should be discontinued if there is an increase in ALT level and signs or symptoms of liver inflammation are observed.1Clinical drug-drug interaction studies of RDV have not been conducted.
In vitro, RDV is a substrate of CYP3A4, OATP1B1, and P-gp and an inhibitor of CYP3A4, OATP1B1, OATP1B3, and MATE1.1
Minimal to no reduction in RDV exposure is expected when RDV is coadministered with dexamethasone (Gilead Sciences, written communication, July 2020).
CQ or HCQ may decrease the antiviral activity of RDV; coadministration of these drugs is not recommended.1
No significant interaction is expected between RDV and oseltamivir or baloxavir (Gilead Sciences, personal and written communications, August and September 2020).RDV should be administered in a hospital or a health care setting that can provide a similar level of care to an inpatient hospital.
RDV is approved by the FDA for the treatment of COVID-19 in hospitalized adult and pediatric patients (aged ≥12 years and weighing ≥40 kg).
An EUAb is available for hospitalized pediatric patients weighing 3.5 kg to <40 kg or aged <12 years and weighing ≥3.5 kg.
A list of clinical trials is available here: RemdesivirIvermectin Adults: The dose most commonly used in clinical trials is IVM 0.2–0.6 mg/kg PO given as a single dose or as a once-daily dose for up to 5 days. Generally well tolerated
Dizziness
Pruritis
GI effects (e.g., nausea, diarrhea)
Neurological AEs have been reported when IVM has been used to treat parasitic diseases, but it is not clear whether these AEs were caused by IVM or the underlying conditions.Monitor for potential AEs. Minor CYP3A4 substrate
P-gp substrateGenerally given on an empty stomach with water; however, administering IVM with food increases its bioavailability.2
A list of clinical trials is available here: IvermectinNitazoxanide Adults: Doses reported in COVID-19 studies range from NTZ 500 mg PO 3 times daily to 4 times daily.3,4 Higher doses are being studied (ClinicalTrials.gov Identifier NCT04746183).
Doses used for antiprotozoal indications range from NTZ 500 mg to 1 g PO twice daily.Generally well tolerated
Abdominal pain
Diarrhea
Headache
Nausea
Vomiting
Urine discoloration
Ocular discoloration (rare)Monitor for potential AEs. Drug-drug interactions may occur if NTZ is administered concurrently with other highly plasma protein-bound drugs due to competition for binding sites.5
If NTZ is coadministered with other highly protein-bound drugs with narrow therapeutic indices, monitor the patient for AEs.NTZ should be taken with food.
The oral suspension is not bioequivalent to the tablet formulation.
A list of clinical trials is available here: Nitazoxanidea Infuse over 30–120 minutes.
b The FDA EUA permits the emergency use of RDV for the treatment of suspected COVID-19 or laboratory-confirmed SARS-CoV-2 infection in hospitalized pediatric patients weighing 3.5 kg to <40 kg or aged <12 years and weighing ≥3.5 kg.6
Key: AE = adverse event; ALT = alanine transaminase; AST = aspartate aminotransferase; CQ = chloroquine; CYP = cytochrome P450; ECMO = extracorporeal membrane oxygenation; eGFR = estimated glomerular filtration rate; EUA = Emergency Use Authorization; FDA = Food and Drug Administration; GI = gastrointestinal; HCQ = hydroxychloroquine; IV = intravenous; IVM = ivermectin; LPV/RTV = lopinavir/ritonavir; MATE = multidrug and toxin extrusion protein; NTZ = nitazoxanide; OATP = organic anion transporter polypeptide; the Panel = the COVID-19 Treatment Guidelines Panel; P-gp = P-glycoprotein; PO = orally; RDV = remdesivir; SBECD = sulfobutylether-beta-cyclodextrin; ULN = upper limit of normal
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Adults: The dose most commonly used in clinical trials is IVM 0.2–0.6 mg/kg PO given as a single dose or as a once-daily dose for up to 5 days. Generally well tolerated
Dizziness
Pruritis
GI effects (e.g., nausea, diarrhea)
Neurological AEs have been reported when IVM has been used to treat parasitic diseases, but it is not clear whether these AEs were caused by IVM or the underlying conditions. Monitor for potential AEs. Minor CYP3A4 substrate
P-gp substrate Generally given on an empty stomach with water; however, administering IVM with food increases its bioavailability.2
A list of clinical trials is available here: Ivermectin
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Call me when you learn the difference between being investigated and approved. Here is what to look for in that lengthy crap you posted. Only instead of remdesivir you should see ivermectin instead. Good luck finding that in there. You will have to look for a long time as it's not there. I did you a big favor and copied only the ivermectin stuff out of that long post you added earlier. And I enlarged, underlined, bolded and italicized the important parts for you.
RDV is approved by the FDA for the treatment of COVID-19 in hospitalized adult and pediatric patients (aged ≥12 years and weighing ≥40 kg).
And if you need new eye glasses or a magnifying glass let us know.
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